PRDM16 REGULATES ARTERIAL DEVELOPMENT AND VASCULAR INTEGRITY

PRDM16 regulates arterial development and vascular integrity

Proper vascular formation is regulated by multiple signaling pathways.The vascular endothelial growth factor (VEGF) signaling promotes endothelial proliferation.Notch and its laguna 3hp dust collector downstream targets act to lead endothelial cells toward an arterial fate through regulation of arterial gene expression.However, the mechanisms of ho

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The Problems of the Defining the Risk: The Case of Mountaineering

A central assumption in sociology is that the view on the risk is essentially a construction rather than a strictly objective perspective.However, this approach viqua-f4 has a tendency to forget objective knowledge and tangible facts.Our research on risks in high mountains compares the available information on risks (scientific literature, safety i

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ANALYSIS OF THE INFLUENCE OF THROMBOEMBOLIC COMPLICATIONS PREVENTION WITH ORAL ANTICOAGULANTS ON BUDGET IN PATIENTS WITH NON-VALVULAR ATRIAL FIBRILLATION

Atrial fibrillation (AF) is a risk factor for thromboembolic complications, requiring administration of vitamin K antagonists (warfarin) or the new oral anticoagulants (apixaban, dabigatran and rivaroxaban).Aim.To assess the influence of apixaban use on the budget as an alternative to warfarin, dabigatran or rivaroxaban use in patients with non-val

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